Project at a Glance

Title: Epidemiological survey of carboxyhemoglobin in nonsmokers in Los Angeles.

Principal Investigator / Author(s): Deane, Margaret

Contractor: Bureau of Occupational Health and Environmental Epidemiology, California Department of Public Health

Contract Number: ARB-847

Topic Areas: Health Effects of Air Pollution


The uptake of carbon monoxide in Los Angeles commuters was measured by determining carbon monoxide concentrations in expired air before and after commuting. Estimates of exposure were made by determining carbon monoxide concentrations in air collected within each car during each trip. There was a definite increase in expired air carbon monoxide concentration during the morning commuting trip, but not during the afternoon trip. No consistent differences by geographic area were noted. The regression of post-commuting expired air carbon monoxide values on ambient air values resulted in statistically significant regression and correlation coefficients. Multiple regression analysis showed that the post-commuting values depended more upon pre-commuting expired air values than upon ambient concentrations of carbon monoxide experienced during commuting. Smokers showed consistently higher values of carbon monoxide than nonsmokers, and the effect of smoking was several times greater than that of exposure to carbon monoxide levels experienced during commuting.

For questions regarding this research project, including available data and progress status, contact: Research Division staff at (916) 445-0753

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