ARB Research Seminar

This page updated June 19, 2013

Biomarkers of Exposure to Airborne Criteria and Air Toxic Pollutants

Rogene F. Henderson, Ph.D., Lovelace Respiratory Research Institute, Albuquerque, New Mexico

June 10, 2004
Cal EPA Headquarters, 1001 "I" Street, Sacramento, CA



Biomarkers are measurements in biological systems that define exposure, biological response, or susceptibility to a toxic compound. A review of biomarkers of exposure to criteria pollutants and selected toxic air pollutants will be presented. While the main emphasis will be on biomarkers of exposure, early physiological changes that are not on the direct pathway to disease, but do indicate an exposure has occurred, will be included in the discussion. There will also be a discussion of susceptible populations and their biomarkers of exposure. Finally, there will be a discussion of the current and future strategies for use of biomarkers of exposure in the context of air pollutants.

Speaker Biography

Dr. Henderson is a Senior Scientist at the Lovelace Respiratory Research Institute, Albuquerque, New Mexico and a Clinical Professor in the College of Pharmacy of the University of New Mexico. Dr. Henderson received her Ph.D. in Chemistry from the University of Texas, Austin and has served or is serving on a number of national committees including: the National Research Council's (NRC) Committee on Environmental Studies and Toxicology, NRC Subcommittee on Biological Markers in Pulmonary Toxicology, Advisory Council of the National Institute of Environmental Health Sciences, Health Effects Institute Research Committee, and US EPAs Scientific Advisory Board Environmental Health Committee.

Dr. Henderson's major research interests are in the use of lung fluid analyses to detect and characterize biomarkers of developing lung disease. Her research also includes the study of the biological fate of inhaled vapors and the use of biological markers to assess the risk from exposure to toxic environmental pollutants. Dr. Henderson has published over 250 articles on her research.

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