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arbcombo -- Peripheral Blood Gene Expression in Subjects with Coronary Artery Disease and Exposure to Particulate Air Pollutants

Posted: 16 Apr 2014 16:04:24
Presentation is available for downloading!

“Peripheral Blood Gene Expression in Subjects with
Coronary Artery Disease and Exposure to Particulate
Air Pollutant Components and Size Fractions”. 

http://www.arb.ca.gov/research/seminars/delfino2/delfino.htm

Ralph J. Delfino, M.D., Ph.D.
University of California, Irvine

Thursday, April 17, 2014 1:30 pm, PDT (WEBCAST)
Sierra Hearing Room, 2nd Floor, Cal/EPA Building
1001 I Street, Sacramento, California

Cardiovascular disease outcomes have been associated with
exposure to ambient particulate matter (PM) air pollution in many
epidemiological studies. Experimental studies have revealed
changes in the expression of key genes with exposure to air
pollution from fossil fuel combustion. We hypothesized that blood
cell gene expression levels along biological pathways relevant to
cardiovascular outcomes would be associated with traffic-related
air pollutant exposures in elderly subjects with coronary artery
disease living in the Los Angeles Air basin.

In the present study data were collected in a cohort panel study
funded by National Institute of Health (NIH), National Institute
of Environmental Health Sciences (NIEHS). Overall, the results
obtained in this study support our hypothesis that
traffic-related air pollutant exposures affect the expression of
genes in pathways that are important to adverse cardiovascular
outcomes.

Announcement and Presentation can be viewed at:
   http://www.arb.ca.gov/research/seminars/seminars.htm

Your e-mail questions will be aired during the
Q&A period.  Please send your-e-mail questions
to:   sierrarm@calepa.ca.gov

Information on this seminar presentation please contact:
   Nargis Jareen at (916) 327-3951 or njareen@arb.ca.gov

Information on the ARB Research Seminar Series please contact:
   Peter Mathews at (916) 323-8711 or pmathews@arb.ca.gov

To receive notices for upcoming Seminars please go to: 
   http://www.arb.ca.gov/listserv/listserv.php
   and sign up for the seminars list serve.


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